[AG Scientific 공식대리점 관련 업무대행/수입] Mitomycin C

Product Information:

Mitomycin C is an alkylating agent produced from Streptomyces caespitosus. It has antitumor properties, inhibiting DNA synthesis and nuclear division of cancer cells, especially Ehrlich ascites tumor cells. It also activates both intrinsic and extrinsic pathways of apoptosis.
 

Mitomycin C specifically targets the guanine nucleoside sequence 5'-CpG-3'. It promotes DNA crosslinking and inhibits separation of complementary DNA strands. Because of this mechanism, it is most active from late G1 phase to S phase of cell cycle.
 

Mitomycin C is useful as an antibiotic for both Gram-negative and Gram-positive bacteria.

• CAS Number: 50-07-7
• Molecular Weight: 334.3
• Chemical Formula: C₁₅H₁₈N₄O₅
• Solubility: Ethanol
• Storage Temperature: -20°C

Specifications:

• Appearance: Blue-violet powder
• Solubility (DMSO; 10mg/mL): Clear, violet solution
• Solubility (CH₃OH; 10mg/mL): Clear, violet solution
• Purity by TLC (NP,CH₂CL₂,CH₃OH 9:1) dETECTION: H2SO4/ Heat: > 99 %
• Purity by TLC (RP C18, CH₃OH, H₂O 9:1): > 99 %
• Purity by HPLC (CH₃OH, H₂O): > 99 %
• Purity by HPLC (RP CH₃CN, H₂O): > 99 %
• UV Analysis (CH₃OH): λmax: 216,360,560 nm
• Storage & Handling: Store desiccated at -20°C